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Shanghai researchers make key findings about obesity gene

English.news.cn   2013-12-14 10:20:14            

By Cai Wenjun

BEIJING, Dec. 14 (Xinhuanet) -- Researchers from Ruijin Hospital have made important discoveries about a gene related to obesity, hospital officials said yesterday.

The discoveries can help provide a new route for obesity prevention and treatment, they said.

The researchers found that the LGR4 gene can have a big influence in the occurrence of obesity.

People with mutated LGR4 genes can have over two times the risk of being obese.

They also found that rats that had the LGR4 gene deactivated had better physical data and lower weights even when fed a fattier diet.

In 2004, doctors from Ruijin started to recruit obese patients below 30 years of age for genetic studies. The team has collected over 1,000 obese people's DNA information and clinical records.

European scientists also have made related findings showing that European offspring whose LGR4 genes are less active weigh less than ordinary people.

Obesity is a disease that carries the risk of complications such as diabetes, hypertension, heart disease and even sudden death.

Experts said obesity has close ties to heredity, which means obese usually have close relatives with the same problem.

(Source: Shanghai Daily)


Study: obesity main contributor to early puberty

BEIJING, Nov. 4 (Xinhuanet) – The greater a young girl s body mass index, the earlier she enters puberty, according to Cincinnati Children’ s Hospital researchers as quoted by media reports Sunday.

Puberty starts at an average age of 9.7 years old in white, and non Hispanic girls, according to the study, which is 4 months earlier than the statistics revealed in 1997. Full story

Scientists: “Obesity gene” makes you fat

BEIJING, July 16 (Xinhuanet) -- Scientists have discovered a gene associated with obesity that triggers hunger to make people fat, according the Journal of Clinical Investigation on Monday.

The discovery follows studies of blood samples from people after meals, combined with functional magnetic resonance imaging of volunteers' brains and cell-based studies looking at the "hormone" ghrelin production at a molecular level. Full story

Editor: Yang Yi
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