Russian Tupolev TU-22 long-range strategic bombers conduct an air strike at an unknown location in Syria, in this still image taken from video footage released by Russia's Defence Ministry on November 18, 2015.

MOSCOW, Nov. 15 (Xinhua) -- Six Tu-22M3 long-range bombers took off from Russia and struck Islamic State (IS) targets near the town of Albu Kamal in Syria's Deir al-Zour province, the Russian Defense Ministry said Wednesday.

The warplanes flew over the territories of Iran and Iraq and destroyed strong points, manpower accumulations and armored vehicles of the terrorist group, it said in a statement.

After fulfilling the combat mission, all the Russian aircraft returned to their base airfields.

On Tuesday, the Russian Defense Ministry issued a statement accusing the U.S.-led coalition of hampering Russian air force operations near Albu Kamal, one of the last IS strongholds in Syria.

The coalition denied the accusations.

The Russian air force is providing support to the advancing Syrian government troops in the east of the country against IS terrorists.