New study shows rise in drug resistance of dangerous infection in U.S. hospitals 2009-12-24 08:05:40   Print

    WASHINGTON, Dec. 23 (Xinhua) -- A new study in the journal Infection Control and Hospital Epidemiology reports a surge in drug-resistant strains of Acinetobacter, a dangerous type of bacteria that is becoming increasingly common in U.S. hospitals. This study is being posted online Wednesday and will appear in the journal's February print edition.

    Acinetobacter infections attack patients in hospital intensive care units and others and have recently plagued soldiers returning home from the war in Iraq. These infections often appear as severe pneumonias or bloodstream infections, and require strong drugs to be treated, when they can be stopped at all.

    Using data from 300 hospitals around the country, researchers at the Extending the Cure project analyzed trends in resistance toimipenem, an antibiotic often reserved as a last-line treatment. The study found that between 1999 and 2006, there was more than a 300-percent increase in the proportion of Acinetobacter cases resistant to the drug.

    "The findings are troubling because they suggest this bacteria is becoming resistant to nearly everything in our arsenal," said Ramanan Laxminarayan, the principal investigator of Extending the Cure, a project examining antibiotic resistance at the Washington, D. C. based think-tank Resources for the Future. "There is a lot of attention on methicillin-resistant Staphylococcus aureus (MRSA), but less on infections caused by bacteria like Acinetobacter for which there are fewer drugs in the development pipeline. While all drug resistance is of concern, it is particularly worrying in the case of bugs for which we have few treatment options."

    To address this growing public health threat, the nation must adopt a comprehensive solution to the problem of antibiotic resistance, the researchers said.

Editor: Lin Zhi
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