WASHINGTON, Nov. 19 (Xinhua) -- Former U.S. Republican presidential candidate John McCain's office said on Wednesday that he would run for re-election as the Arizona Senator in 2010.

    The 72-year-old Senate veteran in his fourth term has met with his advisors on Tuesday, discussing to establish a fundraising political action committee to launch the bid for another six-year term, according to McCain's office.

    McCain lost his second bid for the White House on Nov. 4 to Democratic presidential candidate Barack Obama after he was defeated by George W. Bush in the 2000 presidential primary elections.

    He returned to the Senate on Tuesday for a meeting of Republican lawmakers and was told by his aides to resume full-time service in the Senate after a nearly two-year hiatus for the presidential campaign.

    Political observers said that McCain, unlike some other losers in the presidential elections, would "resist retreating into the wildness, and is instead likely to seek an active role in the Senate" after it begins a new term in January.

    He was also expected to reach across the aisle to work together with the Democratic government after Obama takes over the White House.

    The two met for the first time since the election at the president-elect's transition headquarters in Chicago on Monday, and pledged a "new era of reform" to solve key challenges the country is facing, including the economic crisis, energy policy and national security.

Special Report: U.S. presidential election 2008