BEIJING, June 19 (Xinhuanet)-- Researchers
have successfully saved the life of an advanced skin cancer patient by treating
him with clones of his own immune cells, according to this week's issue of
the New England Journal of Medicine.
Researchers at the Fred Hutchinson Cancer Research Center in
Seattle who treated the dying patient extracted white blood cells, the key
component of the immune system, and grew the infection-fighting T cells in the
laboratory.
The cloned T cells were then reinfused to the patient to
fight the cancer.
The 52-year-old man had recurrent melanoma that failed to
respond to therapy or surgery when he enrolled in a clinical trial.
The disease had spread to his lungs and a lymph node
before he received the two-hour infusion of the lab-grown immune system cells.
Sixty days later, all signs of the disease were gone.
Researchers said the approach might allow them to fight
cancer with safer and less invasive methods than the surgery, radiation and
chemotherapy medications that are often used.
If the new approach is successful in trials, it may be
used to treat 25 percent of all patients with late-stage melanoma similar to the
disease in the study, said Cassian Yee, senior author of the paper and an
associate member of the clinical research division,
Melanoma, typically caused by excessive sun exposure,
starts innocuously. It first appears as a tiny mole but, within a couple of
months, begins growing relentlessly. Gradually, it works its way under the
skin, spreading cancer cells throughout the body.
(Agencies)