 |
|
Britain will put on trial shortly a new IVF (in-vitro fertilization) technique which lets eggs develop in the womb rather than the test-tube straight after fertilization, New Scientist reported Wednesday on its website. (File Photo) Photo Gallery>>>
|
LONDON, Feb. 27 (Xinhua) -- Britain will put on trial shortly
a new IVF (in-vitro fertilization) technique which lets eggs develop in
the womb rather than the test-tube straight after fertilization, New Scientist
reported Wednesday on its website.
The new technique, that allows embryos created in the
lab to be incubated inside a perforated silicon container inserted into a
woman's own womb, was developed by Swiss company Anecova, according to the
report.
In standard IVF, eggs harvested from a woman are
fertilized in the lab and allowed to develop in an incubator for 2 to 5 days.
The healthiest embryos are chosen to be transferred into the uterus. But this
new technique would see fertilized eggs placed in a device which is then planted
in the womb. After a few days the device is taken out and the embryo deemed to
have the best chances of survival reimplanted.
The new device ("silicon womb") that holds test-tube
embryos inside the womb to expose them to more natural conditions provides a
more natural environment and may produce better quality embryos and reduce the
need to harvest so many eggs from infertile women, according to researchers.
The silicon capsule is about 5 millimeters long and
less than a millimeter wide with its walls being perforated with 360 holes, each
around 40 microns across. After embryos have been loaded inside, the ends are
sealed and the container is connected to a flexible wire that holds the device
inside the uterus. A thread trails through the cervix to allow it to be
recovered later on.
With encouraging results from a small trial in
Belgium, British fertility group CARE Fertility in Nottingham starts from
Wednesday recruiting 40 women for the trials, the report said.
Each woman will have between 8 and 12 eggs harvested,
then half their embryos incubated in the lab, and the other half inside the new
device.
The trial in Belgium suggests the embryos produced in
vivo rather than in vitro are of a higher quality, therefore having a better
chance of survival.
Researchers at the CARE Fertility group who are
carrying out the study are keen to find out whether these embryos grown by the
technique have fewer chromosomal abnormalities, in addition to establishing
whether the technique improves the chances of pregnancy.
"We have often wondered whether the rate of
abnormality is higher with in vitro embryos, but we have never been able to
establish this," said Fishel who expressed his belief that embryos grown in the
device will be more resilient, meaning fewer eggs may need to be harvested from
women to achieve a successful pregnancy.
Care Fertility hopes to have an initial results by
May or June, and a clearer picture of how successful the technique is by the end
of year.