BEIJING, Jan. 3 (Xinhuanet) -- Morning gargle could
be used some day as one way for people to find whether they have head and neck
cancer, U.S. researchers said as quoted by media reports Thursday.
Scientists at the Johns Hopkins Kimmel Cancer Center
in Baltimore tried to use mouth rinses that capture genetic signatures linked to
cancer as a screening tools for heavy smokers and alcohol drinkers -- those at
high risk for head and neck cancers.
Patients were asked to brush the inside of their
mouths, then rinse and gargle with a salt solution. The scientists filtered out
cells in the rinsed saliva that might contain one or more of 21 bits of
chemically altered genes associated with head and neck cancers.
"The challenge is to predict which hypermethylated
genes are most specific to cancer," lead investigator Dr. Joseph Califano of
Johns Hopkins Medical Institutions said in a statement.
Since every cancer process involves a unique genetic
fingerprint, Califano predicts combining several gene signatures may identify a
larger percentage of cancer patients than using single ones.
(Agencies)