HONG KONG, Oct. 16 (Xinhua) -- A study found that a substance called
"lupeol" contained in fruits may help beat head and neck cancer, announced the
University of Hong Kong which made the result public here Tuesday.
The study, conducted by the university's Faculty of Medicine, revealed that
lupeol, a compound rich in fruits, selectively targeted and killed cancer cells.
Using a mouse animal model, lupeol dramatically decreased tumor volume and
suppressed local metastasis while bearing minimal effect on surrounding tissue
and other vital organs like liver and kidney.
Interestingly, lupeol was found to be more effective and more potent than
conventionally used chemotherapeutic drug, cisplatin, by approximately
three-fold in terms of tumor volume and degree of metastasis suppression.
Besides, when lupeol was used in combination with cisplatin, the
anti-tumour activity of the chemotherapeutic drug could be enhanced by 40-fold.
The above research result was published in the international scientific
journal Cancer Research in September, 2007.
Head and neck cancer includes cancers of the nose, oral cavity, salivary
gland, etc. In the year 2004, 2,087 new cases were diagnosed in Hong Kong, with
the number of new cases increasing steadily every year.
Human papilloma virus infection, alcohol and tobacco consumption and low
fruits and vegetables intake all contribute to the increased risk of head and
neck cancer development.
The university was in the hope that the findings will also show people that
only a slight change in their everyday meal or a small change in their choice of
food intake may have an astounding impact on cancer prevention and
therapy.