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Nobel laureate James Watson(File
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WASHINGTON, May 31 (Xinhua) -- Nobel laureate James Watson, co-discoverer of the
DNA double helix and father of the Human Genome Project, on Thursday became the
first human to receive the data that encompass his personal genome sequence.
He got a DVD with his full genome data in it in a
presentation at Baylor College of Medicine, Huston, Texas. The 1-million-dollar,
two-month project is a collaboration of the Connecticut-based 454 Life Sciences
and the BCM Human Genome Sequencing Center.
The announcement, aside from its meaning to Watson,
is significant because it demonstrates that it will be possible in the future to
sequence anyone's genome -- a goal toward which many sequencing firms are
working. The time and cost will decrease as the technology improves.
The raw sequencing data was released Thursday to the
publicly available resource called GenBank National Center for Biotechnology
Information Trace Archive.
"When we began the Human Genome Project, we
anticipated it would take 15 years to sequence the 3 billion base pairs and
identify all the genes," said Richard Gibbs, director of the HGSC.
"We completed it in 13 years in 2003 - coinciding
with the 50th anniversary of the publication of the work of Watson and Dr.
Francis Crick that described the double helix. Today, we give James Watson a DVD
containing his personal genome -- a project completed in only two months. It
demonstrates how far the sequencing technology has come in a short time."
Watson is the co-discoverer of DNA's structure and a
1962 Nobel Laureate. "It is only appropriate to work with him on this ambitious
genome sequencing project," said Jonathan Rothberg, founder and former chairman
of 454 Life Sciences.
This project will pave the way for exploring life at
the ultimate level by uncovering what makes each individual unique, according to
Rothberg.
Watson plans to evaluate the information included in
the genome and write about its significance to him, his family and the future of
genetic medicine at a later time.
"There will be a host of ethical and social questions
as we move into the phase of integrating this kind of information into clinical
in the future," said Dr. Amy McGuire, assistant professor of medical ethics at
BCM. She has advised on the ethical issues involved in this personal genome
effort.