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An international team of researchers
reported Thursday that they have sequenced the genome of Aedes aegypti,
the mosquito responsible for transmitting yellow and dengue fevers, which
are a major burden in Africa and other parts of the developing world.
(File Photo)
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WASHINGTON,
May 17 (Xinhua) -- An international team of researchers reported Thursday that
they have sequenced the genome of Aedes aegypti, the mosquito responsible for
transmitting yellow and dengue fevers, which are a major burden in Africa and
other parts of the developing world.
These findings, which will be published in the May 18
issue of journal Science, may provide new leads for controlling the spread of
these diseases, and they offer the opportunity to compare this genome with those
of Anopheles gambiae, the mosquito that transmits malaria.
Based on the draft sequence, the researchers reported
that the two mosquito genomes have much in common but differ in overall size,
the amount of mobile sequences called "transposable elements," and the average
lengths of "introns," which are sequences that do not code for protein. Other
differences involve gene density and the composition of gene families.
These insects represent the two major mosquito
subfamilies, and the differences between them should reflect inherent biological
properties, such as blood feeding preferences, host-seeking behavior and
individual abilities to transmit certain pathogens.
The authors also compared the A. aegypti genome to
that of the more distantly related Drosophila melanogaster and identified
differences that should help clarify which genes and gene activities are
specific to mosquitoes. กก