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BEIJING, April 24 (Xinhuanet) -- Depression appears
to raise the risk for diabetes in elderly people, according to a study in
Monday's Archives of Internal Medicine.
"Older adults who report high levels of depressive symptoms are more likely to develop diabetes over time than
older adults who have lower depressive symptoms," said lead researcher Mercedes
R. Carnethon of Northwestern University.
"We need to carefully evaluate older adults for
depressive symptoms, and they need to be taken seriously because of the
potential impact," she added.
Unlike some other studies examining a link between
depression and diabetes, this one looked at the effects not only of single bouts
of depression but also of chronic depression and depression that worsened over
time. It found an increased risk for diabetes in each of those scenarios.
In the study, Carnethon's group collected data on
almost 4,700 people 65 years of age and older who were not diabetic when the
study began in 1989.
Over the following 10 years, participants were
evaluated for symptoms of depression linked to changes in mood, irritability,
calorie intake, concentration and sleep.
"People who report higher depressive symptoms may not take as
good a care of themselves as they should," Carnethon said.
"For example, they may be less physically active, and
thus more likely to gain weight, which is the primary risk factor for diabetes,"
she added.
But the study statistically accounted for known
lifestyle risk factors for diabetes like being overweight and sedentary, and
still found that depression increased the risk of diabetes.
Carnethon said the findings suggest depression may
play a role in causing diabetes, while biological factors could also be at play.
These include increased levels of blood markers of inflammation, such as
C-reactive protein, which has been linked to both diabetes and depression.
Diabetes is marked by high levels of blood glucose
resulting from defects in the production or action of insulin, which allows
glucose to enter the body's cells for use as fuel.
Howere, more research is needed to identify conclusively
whether depression increases diabetes risk through excessive caloric consumption
and/or through sedentary behavior.
(Agencies)