BEIJING, April 23 (Xinhuanet) -- A new HIV drug by
Pfizer faces safety concerns by U.S. government regulators at a meeting next
week, and if approved, would be the first in a new class of drugs to treat
the virus that causes AIDS.
The Food and Drug Administration will ask a panel of outside experts whether risks of cancer and infection
are serious enough to limit Pfizer's ability to market Maraviroc, a twice-a-day
pill designed to fight HIV. The panel is scheduled to vote Tuesday on whether
the drug should be approved.
The FDA is not required to follow the experts'
recommendation, but it often does.
Maraviroc is in a class of drugs called CCR5
antagonists, which block HIV from entering white blood cells through a pathway
present in the majority of patients who carry the virus.
Pfizer did not uncover any cancerous side effects
while testing its drug on patients, but similar studies by other companies have
raised safety concerns.
British drug maker GlaxoSmithKline plc decided to
scrap its drug aplaviroc in 2005 after signs of liver damage appeared in some
patients.
(Agencies)