BEIJING, May 26 (Xinhuanet) --
Twenty-five years after the first AIDS cases emerged, scientists confirmed in
Friday's edition of the journal Science that the HIV virus first originated in
wild chimpanzees in corner of southern Cameroon.
The study suggested people contract the deadly virus from
chimpanzees by killing and eating them.
A virus called SIVcpz (Simian Immunodeficiency Virus from
chimps) was believed to have been the precursor to HIV, but this virus had only
been found in a few captive animals. The current study has been able to trace a
natural reservoir of the virus.
To solve the mystery of HIV's ancestry, scientists
employed trackers to plunge through dense jungle and collect the fresh feces of
wild apes - more than 1,300 samples in all.
Scientists long have known that nonhuman primates carry
their own version of the AIDS virus, called SIV or simian immunodeficiency
virus. But, it was not known how prevalent the virus was in chimps in the wild,
or how genetically or geographically diverse it was,
The team tested chimp feces for SIV antibodies, finding
them in a subspecies called Pan troglodytes troglodytes in southern Cameroon.
By genetically analyzing the feces, researchers could
trace individual infected chimps. The team found some chimp communities with
infection rates as high as 35 percent, while others had no infection at all.
There are three types of HIV-1, the strain of the human
virus responsible for most of the worldwide epidemic. Genetic analysis let the
team identify chimp communities near Cameroon's Sanaga River whose viral strains
are most closely related to the most common of those HIV-1 subtypes.
The Sanaga River is an important commercial gateway in
this area and it is widely accepted that someone who was infected with HIV made
his way to Kinshasa. The study suggests the virus passed from chimpanzees to
people more than once.
"We don't really know how these transmissions occurred,"
the researchers said.
"We know that you don't get it from petting a chimp, or
from a toilet seat, just like you can't get HIV from a toilet seat. It requires
exposure to infected blood and infected body fluids. So if you get bitten by an
angry chimp while you are hunting it, that could do it."
The first human known to be infected with HIV was a man
from Kinshasa in the nearby country of Congo who had his blood stored in 1959 as
part of a medical study, decades before scientists knew the AIDS virus existed.
In people, HIV leads to AIDS but chimps have a version
called simian immune deficiency virus that causes them no harm. Humans are the
only animals naturally susceptible to HIV.
AIDS was only identified 25 years ago. The virus now
infects 40 million people around the world and has killed 25 million.
Spread via blood, sexual contact and from mother to child
during birth or breast-feeding, HIV has no cure and there is no vaccine yet,
although drug cocktails can help control it. Enditem
(Agencies)