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Natural protein opens door for development of new anti-obesity agent
www.chinaview.cn 2006-04-19 21:44:50

A new study suggests that a  natural protein called ciliary neurotrophic factor (CNTF) might boost the body's fat-burning ability, reported this week's issue of Nature Medicine.
A new study suggests that a  natural protein might boost the body's fat-burning ability. The findings may help in the development of a new anti obesity agent (file photo)
    BEIJING, April 19 (Xinhuanet) -- A new study suggests that a natural protein called ciliary neurotrophic factor (CNTF) might boost the body's fat-burning ability, reported this week's issue of Nature Medicine.

    "While hormones such as leptin were initially thought to be the cure-all for weight loss, they were later found to be ineffective in obesity due to the presence of proteins which inhibit their ability to stimulate fat metabolism. Fortunately, CNTF's effects on fat burning are maintained," Said research leader Dr. Greg Steinberg, of the University of Melbourne in Australia, in a statement.

    Steinberg's team found that CNTF activates an enzyme called skeletal muscle AMP kinase, which in turns boosts the body's ability to metabolize fat and sugar. 

    Until recently, most obesity research has concentrated on the regulation of appetite by hormones such as leptin.

    The findings may help in the development of a new anti obesity agent. 

    "Dr. Steinberg's finding is significant because this new pathway that overcomes leptin resistance opens the door to a more promising avenue for the development of a therapeutic anti-obesity agent," said Dr. Diane Finegood, a Canadian scientist.Enditem

    (Agencies)

Editor: Yang Li
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