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OTTAWA, March 16 (Xinhuanet) -- Bioengineers at the University of Calgary in
Canada have successfully grown insulin producing cells in a lab, marking a major
breakthrough in diabetes research.
Scientists hope to eventually transplant lab-grown, insulin producing cells
directly into the bodies of patients with Type 1 diabetes and free them from
injections, Canadian Television reported on Thursday.
Type 1 diabetes makes the body unable to produce enough insulin, requiring
those suffering from the disease to inject themselves with the hormone.
In theory, the transplant would eliminate the need for daily insulin
injections by patients who suffer from the disease.
"This transplant procedure, developed in Edmonton, is the best thing to
come in 20 years to treat type one diabetes," said Dr. Leo Behie, the professor
of chemical engineering in charge of the research project.
Although there are still many steps to be taken including clinical trials,
the tests that Behie and his team have done in his lab so far are very
encouraging.
In many cases people are now off insulin and they have good sugar controls
in their blood with no constrains in terms of eating. "That is a big deal," said
Behie.
The research stems from a project by New York-based Juvenile Diabetes
Research Foundation International (JDRF).
Donna Lillie, of the Canadian Diabetes Association, said the research
presented a real possibility for people with Type 1 diabetes to get rid of their
multiple daily injections.
"Dr. Behie's all-Canadian team has brought us one more step toward
potentially securing a large supply of insulin-producing pancreatic cells for
transplantation into individuals with Type 1 diabetes," Lillie said.
University of Alberta scientists transplanted cells into Type 1diabetes
sufferers in 2000, freeing some from injections over the last five years.
But the approach they used required pancreas cells from as manyas three donor
cadavers which created a supply headache. Even with the supply, only 10
percent were able to stop taking insulin injections.
Behie said his plan to produce cloned cells on a large scale
incomputer-controlled bioreactors would "get rid of this supply bottleneck."
He said his goal was to provide Type 1 diabetes sufferers with a reliable
supply of cells that eventually could be given through booster shots. Enditem
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