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BEIJING, Nov. 4 (Xinhuanet) -- 10
million people worldwide have a heart attack each year, and Aspirin is a
standard emergency treatment. But a British study released Thursday said that
adding the drug clopidogrel could save more lives.
The study, by Dr Zheng-Ming Chen and scientists at
the University of Oxford in England, found that clopidogrel -- sold by
Bristol-Myers Squibb under the trade name Plavix -- provides a benefit to
heart-attack patients with an elevated ST-segment reading on an
electrocardiogram.
In contrast, earlier studies indicated a benefit only
in patients without this EKG reading.
"If early clopidogrel therapy was given in hospitals
to just 1 million of the 10 million patients who have a heart attack every year
then it would, on present evidence, prevent about 5,000 deaths and 5,000
non-fatal reinfractions (repeat heart attacks) and stroke," Chen said in The
Lancet medical journal.
The researchers compared the impact of the drug
against a placebo, or dummy pill, on 45,800 patients treated for heart attacks
at 1,250 hospitals in China.
In patients who received 75 milligrams of the drug
daily, in addition to an aspirin or other treatment for four weeks, there were 7
per cent fewer deaths than in the placebo group and a 14 per cent drop in repeat
heart attacks.
The British Health Foundation said the research was
the latest of several studies showing the benefits of the drug for patients with
vascular disease and also for those who have had heart attacks.
(Agencies) |